Jamie E. Collins

I am the Senior Biostatistician at OrACORe and Assistant Professor in the Department of Orthopedic Surgery at Harvard Medical School. I received my Masters degree in Mathematics from Boston University in 2005 and spent 5 years as a statistician and statistical programmer at a statistical consulting company. I joined OrACORe in 2009 and did my pre-doctoral work as a fellow in the Clinical Orthopedic and Musculoskeletal Education and Training (COMET) Program, earning my PhD in Biostatistics in 2014. Dr. Elena Losina served as my dissertation advisor. My dissertation, Informative Censoring with an Imprecise Anchor Event: Estimation of Change over Time and Implications for Longitudinal Data Analysis, focused on the phenomenon of informative censoring. I investigated approaches to detecting informative censoring and considered whether incorporating information about total knee replacement can improve estimates of disease progression in knee osteoarthritis.

My research interests include the analysis of multilevel and correlated data, missing data and informative dropout, group based trajectory and latent growth curve models, and risk prediction. My work in health services research in osteoarthritis includes outcomes research for patients with total joint replacement, applying novel methods to estimate disease progression over time, and in identifying and classifying biomarkers for progression of knee osteoarthritis.

Most recent publications:

Hunter D, Nevitt M, Lynch J, Kraus VB, Katz JN, Collins JE, Bowes M, Guermazi A, Roemer FW, Losina E; FNIH OA Biomarkers Consortium. Longitudinal validation of periarticular bone area and 3D shape as biomarkers for knee OA progression? Data from the FNIH OA Biomarkers Consortium. Ann Rheum Dis (2016). PMID: 26483253

Klara K, Collins JE, Gurary E, Elman SA, Stenquist DS, Losina E, Katz JN. Reliability and Accuracy of Cross-sectional Radiographic Assessment of Severe Knee Osteoarthritis: Role of Training and Experience. J Rheumatol (2016). PMID: 27084912

Smith SR, Deshpande BR, Collins JE, Katz JN, Losina E. Comparative pain reduction of oral non-steroidal anti-inflammatory drugs and opioids for knee osteoarthritis: systematic analytic review. Osteoarthritis Cartilage (2016). PMID: 26844640

Losina E, Collins JE. Forecasting the future pain in hip OA: can we rely on pain trajectories. Osteoarthritis Cartilage (2016). PMID: 26854793

Losina, E., Collins, J.E., Wright, J., Daigle, M.E., Donnell-Fink, L.A., Strnad, D., Usiskin, I.M., Yang, H.Y., Lerner, V. and Katz, J.N. Postoperative care navigation for total knee arthroplasty patients: A randomized controlled trial. Arthritis care & research (2016). PMID: 26714179

Collins JE, Deshpande BR, Katz JN, Losina E. Race and sex specific incidence rates and predictors of total knee arthroplasty: Seven year cumulative data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2015 Nov 10. PMID: 26554629

Dave AJ, Selzer F, Losina E, Klara KM, Collins JE, Usiskin I, Band P, Dalury DF, Iorio R, Kindsfater K, Katz JN. Is There an Association Between Whole-body Pain With Osteoarthritis-related Knee Pain, Pain Catastrophizing, and Mental Health? Clin Orthop Relat Res. 2015 Dec; 473(12):3894-902. PMID: 26443774

Eckstein F, Collins JE, Nevitt MC, Lynch JA, Kraus V, Katz JN, Losina E, Wirth W, Guermazi A, Roemer FW, Hunter DJ. Cartilage thickness change as an imaging biomarker of knee osteoarthritis progression – data from the FNIH OA biomarkers consortium. Arthritis Rheumatol. 2015 Aug 28. PMID: 26316262

Losina E, Ranstam J, Collins JE, Schnitzer TJ, Katz JN. OARSI Clinical Trials Recommendations: Key analytic considerations in design, analysis, and reporting of randomized controlled trials in osteoarthritis. Osteoarthritis Cartilage. 2015 May; 23(5):677-85. PMID: 25952341

Ritter SY, Collins J, Krastins B, Sarracino D, Lopez M, Losina E, Aliprantis AO. Mass spectrometry assays of plasma biomarkers to predict radiographic progression of knee osteoarthritis. Arthritis Res Ther. 2014; 16(5):456. PMID: 25287745

Collins JE, Katz JN, Dervan EE, Losina E. Trajectories and risk profiles of pain in persons with radiographic, symptomatic knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2014 May; 22(5):622-30. PMID: 24662734

For more publications please review my NCBI bibliography.