Adding Value in Knee Arthroplasty

The goals of the AViKA study are to estimate the value of total knee replacement (TKR) care delivery for BWH patients and to identify factors that improve value in the delivery of TKR.

BWH Wellness Initiative

B-Well is a research study aimed at increasing physical activity among Brigham and Women’s Hospital employees by providing monetary rewards.

COMET (T32 Training) Program

The Clinical Orthopedic and Musculoskeletal Education and Training (COMET) Program (an NIH-funded T32) is intended to train highly qualified pre- and postdoctoral trainees in rigorous clinical research methodology to address pressing problems relating to orthopedic and musculoskeletal disorders.

Meniscal Diagnosis in Osteoarthritis

This project is a cross-sectional study aimed at evaluating the diagnostic accuracy of the clinical history and physical examination in patients with symptomatic meniscal tears in the presence of knee osteoarthritis.

Meniscal Tear in Osteoarthritis Research

This study is a multi-center randomized controlled trial that compares the efficacy of arthroscopic partial meniscectomy with postoperative physical therapy versus physical therapy alone in the setting of meniscal tear and knee osteoarthritis.

Injections for the Joint: Experiences and Concerns with Treatment

INJECT is a qualitative study that investigates patients’ attitudes towards having intra-articular injection treatments for osteoarthritis.

Osteoarthritis Registry of Biomarkers and Imaging Trajectories

In order to better understand how osteoarthritis of the knee changes over time and how it affects the lives of patients, we are creating a registry of osteoarthritis patients to collect data on the progression of osteoarthritis.

Osteoarthritis Policy Model

The research team built and validated a state-transition computer simulation model to evaluate the epidemiologic factors that impact knee OA and the societal burden caused by the disease.

OA Risk C

OA Risk C is an interactive risk calculator that predicts a user’s likelihood of developing knee osteoarthritis and of undergoing total knee replacement (TKR) based on demographic and clinical factors.

Pilot Research Incubation and Development Program (PRIDE)

The overarching goal of this program is to provide seed funding and methodologic support for innovative and rigorous clinical and translational research in the Department of Orthopaedic Surgery at BWH.

Study of Hip and Knee Replacement Infection Defense (SHielD)

SHielD examines current practices related to the prophylactic prescription of antibiotics before dental procedures for patients with total hip or total knee replacements.

Study of Physical Activity Rewards after Knee Surgery

SPARKS is a pilot randomized controlled trial applying behavioral economic interventions to patients undergoing total knee replacement (TKR) with the goal of increasing physical activity after surgery.

Study of Total Knee Arthroplasty Responses

STARs seeks to recruit a robust cohort of patients undergoing total knee replacement (TKR) at several sites across the country to supplement data from the AViKA study and to identify factors that improve value in the delivery of TKR.

Spinal metastasis TReatment In DEtermining ambulatory Status (STrIDeS)

STrIDeS examines independent ambulation in patients with spinal metastases. The study aims to evaluate the factors associated with independent ambulation, then to investigate how patients engage in decision-making regarding treatment for spinal metastases.

Treatment of Meniscal Problems in Osteoarthritis

TeMPO is a multicenter randomized controlled trial that aims to evaluate non-operative, non-medication treatment for persons with meniscal tear in the setting of knee osteoarthritis.