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Adding Value in Knee Arthroplasty

Analysis of the data gathered in this study will provide insight into factors related to improving the value of total knee replacement.

The Clinical Orthopaedic and Musculoskeletal Education and Training Program

The COMET Program (an NIH-funded T32) is intended to train highly qualified pre- and post-doctoral trainees in rigorous clinical research methodology to address pressing problems relating to orthopaedic and musculoskeletal disorders.

Inflammation and Osteoarthritis at the Brigham

INFORM examines the interplay of inflammation and obesity in the development and progression of osteoarthritis using ultrasound and synovial fluid aspiration.

Injections for the Joint: Experiences & Concerns with Treatment

The INJECT project (INjections for the Joint: Experiences and Concerns with Treatment) investigates patients’ attitudes about having intra-articular injection treatments for knee osteoarthritis (OA) and providers’ perceptions of the utility of these treatments.

Meniscal Tear in Osteoarthritis Research

MeTeOR is our randomized controlled trial of surgical (arthroscopic partial meniscectomy) vs. non-surgical (physical therapy) treatment for meniscal tear.

Osteoarthritis Policy Model

Our research team built and validated a state-transition computer simulation model to evaluate the epidemiological factors that impact knee OA and the societal burden caused by the disease.

Osteoarthritis Registry of Biomarker and Imaging Trajectories

In order to better understand how osteoarthritis of the knee changes over time and how it affects the lives of patients, we are creating a registry of osteoarthritis patients to collect data on the progression of their disease.

Pilot Research Incubation and Development Program

The overarching goal of this program is to provide seed funding and methodologic support for innovative and rigorous clinical and translational research in the Department of Orthopaedic Surgery at BWH.

Study of Hip and Knee Replacement Infection Defense

SHielD examines current practices related to the prophylactic prescription of antibiotics before dental procedures for patients with total hip or total knee replacements.

Spinal Metastasis Treatment In Determining Ambulatory Status

STrIDeS examines independent ambulation in patients with spinal metastases. The study aims to evaluate the factors associated with independent ambulation, then to investigate how patients engage in decision-making regarding treatment for spinal metastases.

Treatment for Meniscal Problems and OA

TeMPO is a multi-center randomized controlled trial that aims to evaluate non-operative, non-pharmacological treatment for persons with meniscal tear in the setting of knee osteoarthritis.

The Osteoarthritis Prevention Trial

TOPS is a multi-center randomized controlled trial that evaluates knee osteoarthritis prevention strategies in at-risk females compared to a control population.

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